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Medicines & Health

In clinic, it is used in assistant cure of carnitine lacking, cardiovascular diseases, fatty liver, diabetes, immunity lesion, kidney dialysis and blood fat reducing, etc.
In health care, it can resist fatigue and anoxia, lose weight and strengthen physical fitness.

Main use:

1. Healthy weight reducing: high concentration carnitine can accelerating the burning of fat. It is safe for long use.
2.Support and protect liver and kidney.
3.To infant: infant is incapable to biosynthesize carnitine, so it is better to supply carnitine to infant or child when he is younger than 2 years old.
4. Improve performance of sportsman: increase energy supply to cardiac and skeletal muscle , reduce concentration of lactic acid in blood plasma.
5. Adjust internal secretion: dispel splash on face, ameliorate menopause syndrome, and supplementally cure male infertility.
6. Improve immunity, extend life of immunocyte.
7. Decompose long-chain fatty acid, reduce blood fat.

Food additive

As new-type functional food additive, carnitine has been well accepted all over the world. Our state ministry of health has listed it as nutrition supplement. Now it is mainly used in baby milk powder, sports drink and weight reducing food, etc.
In recent years, more and more people are concerning about the important role of L-carnitine in baby's nutrition. L-carnitine needed by people are mainly from food or biosynthesis. Infant is incapable to synthesize sufficient carnitine for his normal metabolism, and has to get carnitine from mother milk. Howerver, for the change of social environment, many mothers have no sufficient milk to feed their babies, or they have no time to feed their babies for they have to work. Many infants have to be fed with milk powder, so L-carnitine should be added in babies' food. Many tests have improved that the added L-carnitine can promote the oxidation of fatty acid, and is good for babies' storage of nitrogen. Therefore, L-carnitine is necessary nutrition for infant.
For L-carnitine can promote the fat matabolism and accelerate energy producing, it is also additive of weight reducing food and sports drink. In 1989, French government has allowed L-carnitine as multi=purpose nitrition, and our state ministry of health has also listed L-carnitine as nutrition supplement. Recently, nutriment with L-carnitine has appeared in domestic market.

Feed addtive

Carnitine can promote animals's growth. Tests have shown that added carnitine can apparently promote the growth of herbivore, so it can be added in the feedstuff for chicks, pigs and fishes.

Sort	Animal	Dosage (mg/kg)	Function
Livestock	Boar	250	strenthen constitution, promote sexual maturity and activity.
	Sow (ten days before giving birth to ablactation)	40	Promote lactescence, shorten the interval between ablactation and hybridization.
	Porket	300-500	Weight increasing
	Early ablactated pig (<28d)	50	Ease the stress reaction of pig at the early state of ablactation
	Normal ablactated pig (>=28d)	30-50	Weight increasing and heighten feed efficiency
	Hog	30-50	Increase protein diposit and muscle rate
Poultry	Chicken (1 week)	150	Help chicken use fat in yolk as energy
	Hen	50	Imcrease hatching rate of eggs
	Layer	50	improve egg produce
	Flesh chick	50	Reduce fat, resis fatty liver caused by abnormal fat metabolism
	Turkey	60
Aquatic products	Fry	250	Increase weight of fishes and prawns, reduce feedstuff consumption, strenghten immunity of aquatic animals, improve health, survival rate and flesh taste of fishes and prawns.
	Common perch, carp, bream fish, tilapia	100－400
	Salmon, brown trout	300－1000
	Siluroid	300
	Young prawns	200－300
	Grown prawns	150－200
	Crab	200－250

Product-choosing

Carnitine can be divided into three kinds:

1. Original products
DL-Carnitine hyarochloride	L-carnitine hydrochloride
DL-carnitine	L-carnitine

2. Acylated products
L-Acetyl carnitine hyarochloride	N-Acetyl carnitine
L-Propionyl carnitine hyarochloride	Dipropylacetyl-L-Carnitine hyarochloride
Glutaryl-L-Carnitine hyarochloride	Acetyl propionyl carnitine hyarochloride
β-Oxidated glutaryl carnitine hyarochloride	Fumaryl-L-Carnitine hyarochloride
Glutamyl-L-Carnitine hyarochloride

3. Compound salts
L-Carnitine tartrate	L-carnitine fumarate
L-carnitine citrate	L-carnitine glutaminate
L-carnitine orotate	L-carnitine palmitate
L-carnitine malate

How to choose carnitine:

Choose on the functions of products

Acylated carnitine has a high purity. It is easy to be absorbed by human body owing to the functions of acylated transferase. It is mostly used in medicine.

Owing to the products' modification, compound salts series of carnitine is not easy to absorb moisture in the air. It has more choices in the taste. Used in producing capsule, tablet, powder, biscuits, solid drink. But pay attention to the ratio of L-carnitine in the compound salts.

Original products of carnitine:DL-Carnitine hyarochloride is the carnitine racemthe that are not separated. It is used for whetting the appetite and adjusting the functions of stomach and intestine. At present, L-carnitine can only be used in feedstuff additive for its biologicalactivity.

As original products, L-carnitine and L-Carnitine hyarochloride are applicable to the above uses. Owing to its strong moisture absorption,it is applicable to making drinks, injection, capsule, tablet and others. It is widely used in feedstuff for its high content of carnitine.

How to choose nutrition supplement

GB2760-96,the maximum use level of this product is as following:

Kind	Range of application	Maximum use level
L-Carnitine tartrate	Chewing tablet, drink and capsule	250－600mg／ tablet, vial,pill
L-Carnitine	Milk powder	300－400mg／KG
	Fruit dink, milk drink	600－3000mg／KG
	Note:Based on L-Carnitine:L-Carnitine tartrate is calculated into L-carnitine

	Coefficient:0.68

"Toxicity" ADI 20mg/kg

Suzhou Huarui Biological Technology Co., Ltd.

Zhangjiagang Tianyi Chemical Co., Ltd.

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